Monday, July 1, 2013

Hepatitis B is not far away from liver cancer?

Tags

How far away from the hepatitis B liver cancer?

Who is the number one killer of liver cancer?

The cause of primary liver cancer is very broad, cirrhosis ranked first, followed by the liver. According to statistics, cirrhotic patients without treatment into the chance of liver cancer increased by 3% per year, and most of cirrhosis from hepatitis B is evolved. About 85% of the clinical liver cancer patients with hepatitis B, especially more than 40-year-old male patient with hepatitis B, mainly because of persistent infection with hepatitis B virus, inflammation promote fibrosis leading to cirrhosis and even liver cancer.

In other countries, a major cause of liver cancer is hepatitis C and alcoholic hepatitis, hepatitis B is very low proportion. In China, with the hepatitis B virus gradually brought under control, the future is also possible to get rid of 'hepatitis - cirrhosis - liver cancer' trilogy model of the disease. But within 30-50 years there will not be much change in the current hepatitis B virus infection after accounting for one tenth of the population, and chronic virus is difficult to remove, so prevention of hepatitis B is the key.

Early symptoms of liver cancer occult

"Occult disease liver cancer early, almost no obvious symptoms, such as appear pale yellow, liver pain, etc. have been developed to explain the disease more serious stage. Most patients in their daily lives if they feel some mild fatigue or weight loss, are do not particularly care, especially in rural and other health conditions are more backward areas, a serious lack of awareness of health care, many patients with liver cancer treatment have to wait until the close late. "Guoya Bing said.

Hepatitis B how to "help cancer as abuse"?

Inflammation increase the chances of cancer

If the hepatitis B virus is difficult to remove, damage to liver cells, causing inflammation in the participation of a large number of inflammatory cytokines, tissue and organ destruction, the environment changes, the opportunity to become cancerous inflammation itself is even greater. Due to the strong ability to repair the liver, inflammation of the tissues and organs to repair damage, and hepatitis C virus replication by interfering with the normal cell DNA, causing liver cell malignant proliferation in the process may eventually grew into a tumor in it. Furthermore, long-term chronic liver inflammation caused by proliferation of fibrous tissue, fibrous tissue hyperplasia will cause cirrhosis, the liver function is impaired.

Inflammation and cancer the same thing

"Although the destruction and destroy cancer inflammation different, but the final outcome is the same." Said Professor Guo Yabing, "inflammation mainly liver fibrosis in a way that deformation hardening, while cancer is the spread of invasive tumor cell proliferation crazy liver, but the outcome is liver failure, so as important as the treatment of inflammation and cancer.

Hepatitis is one of the culprits cause liver cancer recurrence?

Professor Guo Yabing said: "HCC recurrence rate of 50%, generally 3-5 years easy to relapse, and in the treatment of liver cancer, the presence of inflammation affects the entire process of treatment of liver cancer, studies show that aggressive treatment of hepatitis B can simultaneously reduce tumor recurrence risk. 

Anti-cancer screening ferret out hidden liver cancer

Blood plus B super easy to ferret out early HCC

Professor Guo Yabing suggest that you: The usual physical examination, blood tests two pairs of semi hepatitis, liver function and serum alpha-fetoprotein, liver B-plus, the general case of liver cancer can be detected if they are high-risk groups, but also can effectively screening of liver cancer.
Because hepatitis B is induced liver cancer risk factors, do two pairs of semi-hepatitis B can check to determine whether the specific circumstances of HBV infection and infection; liver function tests are mainly looking transaminase indicators to understand whether they are acute liver cell damage; whereas alpha-fetoprotein as liver cancer markers can be detected early HCC; liver B-ultrasound is observed liver conditions, to see whether there is cirrhosis, liver cancer. 

Escape "HCC Trilogy" is the key to periodic review

If you are hepatitis B virus carriers, is generally recommended once a year to review, because normal liver function, almost no inflammation, so do not special treatment. As to whether it will translate into hepatitis, mainly determined by the individual's immune status. If you have hepatitis B patients should be done once every three months to check liver, active treatment, during treatment and continue to observe its effect, and so on. For the development of liver cirrhosis patients, the treatment is the key to prevention and treatment into the liver, rather than treating cirrhosis.

HCC will not be contagious?

A lot of people there is a misunderstanding that the same contagious liver cancer and hepatitis B each other, Professor Guo Yabing joked: "If the cancer cells enter the human body, it may not be able to survive, the cancer itself is not contagious As the mother of the child is also suffering from liver cancer. the liver, which is determined by the genes belonging to genetic factors rather than infection proceeds, of course, will be accompanied by the spread of hepatitis B virus in patients with liver cancer, hepatitis B infection but not the liver cancer. "

B-see tumors? ≠ hepatocellular liver hemangioma
Not once and for treatment of liver cancer

HCC tumor size fits ≠ heal
Professor Guo Yabing pointed out that the high recurrence rate of liver cancer, generally 3-5 years easy to relapse, which relates to a matter of underlying diseases, tumors are not all that is needed across the board, a lot of liver cancer are based hepatitis, cirrhosis of the above, the removal of only part of the treatment, liver problems still not fully resolved, we should be looking into a chronic disease, ongoing treatment of hepatitis B, cirrhosis, and long-term follow-up track.

Early liver cancer cure can fight

Higher cure rate of early liver cancer, liver function generally in good condition, you can choose surgical removal of the tumor, if the patients themselves poor liver function, liver remaining after the cut off is not enough, it is possible postoperative liver failure. Second, it can also be used in liver transplantation, but the indications for surgery are more demanding and costly. In addition, the minimally invasive treatment such as radiofrequency ablation, which allows local heat, inactivation of the tumor in situ, tumor smaller when using this method and surgical resection can achieve a similar purpose.

With survival in advanced

If the cancer development to the mid, you can choose with survival, on the one hand, the treatment is to limit tumor growth, for example by way of plugging tumor blood vessels to inhibit tumor cell growth, the larger part of the tumor resection may choose to reduce tumor volume, or is used topically, autoimmune cell therapy, immunomodulatory agents such as interferon treatment.

The development of late become very difficult to control the disease, there is no effective drug treatment of advanced liver cancer, the survival rate is very low, so early detection, early prevention is important.

Artikel Terkait