Wednesday, June 19, 2013

Precancerous lesions equal to cancer?

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Precancerous lesions does not mean cancer

Precancerous lesions evolve into cancer risk is only about 3%

Precancerous lesions and "cancer" word hook, inevitably there is some relationship was identified between the two, in fact, a precancerous lesions are not cancer, and early signs of cancer nor the same concept. Precancerous lesions is a disease, the development process, with no stability. Like some benign lesions, to intervene early if treatment is reversible condition, if not effectively controlled, it is possible in the direction of the development of cancer. But the likelihood of it?
"We are familiar with atrophic gastritis, gastric ulcer, gastrointestinal polyps, etc., which are associated with gastric cancer, but they really evolved into the possibility of cancer, but only 2% to 3%." Professor Liao Zhener analogy, "said Like cancer, genetic testing, we can predict cancer risk subjects', but even measure up to 80% risk of cancer, we can not determine whether the cancer will really happen, precancerous lesions and cancer does not draw equal sign. "

Precancerous lesions found early cancer of the road block

Some might think that since the precancerous lesions and cancer far away, but so why bother crown "precancerous" scary? In fact, as we can not be sure that the future of cancer precancerous lesions, we can not rule out the possibility that it will eventually move towards cancer, precancerous lesions and positively define treatment can maximize cancer risk aversion.

What are common precancerous lesions

Not all polyps are precancerous lesions
In recent years, often pop out like "small change of colorectal polyps," the relevant reports, does that mean that all precancerous polyps should be included in the ranks? Professor Liu denied, he said, we must first determine the definition of precancerous polyps pathological type, if it is inflammatory polyps or adenomatous hyperplasia, need not nervous. But if it is part of adenomatous polyps, it is possible in the direction of the development of malignant tumors, clinical interventions should be actively treated. Therefore, when polyps larger than 5 mm, it is necessary to confirm pathological biopsy, and when it is more than 8 mm or 1 cm, it is recommended that direct endoscopic resection.

Do not magnify the definition of precancerous lesions

Atrophic gastritis, cervical erosion, ulcers ...... although both of these diseases may be associated with cancer, but they evolved from common diseases to evolve again precancerous condition precancerous there quite a long distance, and whether it will extend This section also go great uncertainty.

So, in addition to the polyps, there is a common disease which can be called precancerous lesions it? Generally include moderate to severe atrophic gastritis, greater than 1 cm and after therapy ulcers, leukoplakia, breast cystic hyperplasia and certain high likelihood of malignancy so benign. In addition, infectious diseases and cancers, such as chronic hepatitis B virus infection or HPV infection-induced hepatitis disease and so can not be called precancerous lesions, because they from the "pre-cancerous" There is a long process.

Reversible precancerous lesions may be terminated

May terminate the development of precancerous lesions
"We need to do is to stop precancerous lesions forward." Professor Liu stressed that "pre-cancerous lesions can be reversed by medical intervention, the exact expression should be actively treated lesions may be terminated in certain states, it does not go malignancies direction. "

For example atrophic gastritis, if the patient is only a superficial gastritis, generally only given dietary and lifestyle guidance, or is in the moderate stage, the drug is added to protect the gastric mucosa. However, if the development of severe atrophic gastritis, and even heterosexual hyperplasia, then you should be vigilant, in addition to the appropriate drug intervention, but also every three months to six months to accept correlation detection gastroendoscopy and tumor markers, etc. will be strangled in the cradle of precancerous lesions.

Older than 40 years should undergo regular cancer prevention medical

Examination is found the most effective means of precancerous lesions, Professor Liu suggestions: older than 40 years of age who have regular cancer screening is necessary. In addition, there is a family history of cancer or cancer-prone areas from the crowd, and some of the staff and regular contact with carcinogens such as miners, etc. should be targeted single disease cancer investigation. General anti-cancer screening, including low-dose spiral CT, gastroscopy, mammography, tumor markers, etc. These can not only detect cancer, but also can detect benign lesions.

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