"Hit" in the increase of breast cancer in pregnant women
What is pregnancy lactation breast cancer?
Medicine during pregnancy or postpartum was diagnosed with breast cancer a year, also known as pregnancy lactating breast cancer. Because of their special physiological period is misdiagnosed, often has to be found in an advanced stage, and because of cancer development and treatment will affect the health of her unborn child, pregnant women will therefore not only difficult decision whether to continue the pregnancy, the doctor of their Treatment will feel very tricky.
Women postpone childbearing age or a hidden
Breast cancer and childbirth have a certain relationship with the high incidence of breast cancer younger, and the probability of modern women postpone childbearing age, pregnancy detection of breast cancer is rising year by year, the majority of women become worthy of attention thing.
Not long ago, Sun Yat-sen Memorial Hospital on the series to a few unfortunate mothers - often feel uncomfortable after Chan pregnancy breast swelling, someone who told her it was normal breast hyperplasia, without worry. But once accidentally touched her own left breast has a lump, to the hospital for a check is actually breast cancer;
Wang suddenly found five months pregnant when breast somewhat haemorrhagic thought it was caused by endocrine disorders before birth, there is no detailed investigation. But the next few months she was constantly bleeding nipples, family members alarmed. On examination, she had breast cancer, the tumor has 3 cm; Sharon belongs to late marriage, married for three years before finally conceive a child, three months pregnant when the doctor told her that her child might not hold up, because her Breast cancer has come to late
Survival or fertility?
Recommend trimester termination of pregnancy found
Faced with the threat of breast cancer, pregnant women need to give up the issue of pregnancy is probably the most talked about. Sun Yat-sen Memorial Hospital, deputy director of the Department of Breast Medical Oncology Diagnostics Division Raonan Yan said the pregnant woman's fertility and survival of breast cancer does not conflict with, or need to terminate the pregnancy and pregnancy related. For breast cancer patients the first three months of pregnancy, doctors generally recommend stopping pregnancy.
If insists students, how to do?
If you insist on continuing trimester of pregnancy if the patient needs to be a mastectomy and axillary lymph node dissection. Then, in the mid-gestation into three months, adjuvant chemotherapy. After giving birth, then radiation therapy and endocrine therapy; If discovered late in pregnancy breast cancer, you should determine the order of surgery and chemotherapy according to tumor size. If the patient is breast-conserving surgery implemented, then radiotherapy after childbirth. Endocrine therapy and targeted therapy can also be carried out after the re-birth; within the last month of pregnancy discovered breast cancer, the fetus before birth can be a variety of follow-up treatment.
Chemotherapy will not harm fetal health?
Because of the relationship of the fetus, the existing breast cancer treatment during pregnancy have some restrictions on the use of breast cancer, endocrine therapy, such as radiation therapy can not be used throughout pregnancy, chemotherapy need to be used in pregnancy after three months, targeting Treatment effects on the fetus is not yet clear. Raonan Yan said, gestational breast cancer chemotherapy drugs with conventional chemotherapy dose intensity without distinction, as chemotherapy will not pose a threat to the health of the fetus, she said: "Many retrospective studies have shown the second trimester chemotherapy mother output baby in good health, an adult disease and cancer incidence has not increased, but more how long-term effects are not yet known. "
Pregnant women how to avoid the "coincidence" of breast cancer?
Who is most at risk?
Raonan Yan said, there are no studies in pregnant lactating breast cancer patients with genetic testing, not sure what kind of people are at high risk. Many people will pregnancy breast lumps as a natural phenomenon, but if lumps hardness, and is gradually increasing, even when we should be alert to the occurrence of breast nipple haemorrhagic. Lactating women often occur due to mastitis, breast lumps, if the lump does not disappear after lactation, and the trend has changed, it should be further examination. Do not trust the various "come" from experience, identify problems and to find a specialist
Breast enlargement is difficult pregnancy detection of breast self-examination
Breast lump is an important basis for the diagnosis of breast cancer pregnancy lactation, excessive swelling of the breasts during pregnancy, but women find breast lumps just become an obstacle. During pregnancy, the breasts undergo the process once again developed for fertility, lactation prepare, then will expand the breast duct epithelium occurs, there will be acinar duct, so that the whole breasts become swollen. "At this point if you do feel it is difficult to rely solely on the hand of a palpable mass." Raonan Yan believes breast examination during pregnancy
Women must be done prenatal breast B-
"A lot of people did not do prenatal breast examination, in fact, for the first time on the use of prenatal ultrasound breast B, B-no harm to the fetus during pregnancy can be used repeatedly. Do not recommend using mammography and MRI. Pregnant women very dense mammary glands, the positive rate of mammography is low, prone to false negatives, a problem may not be discovered, can also cause the effects of radiation on the fetus. unless highly suspected breast cancer and only B-NMR consideration can not be confirmed Check the ".
Pregnancy, lactation: attention to regular breast examination
A quick surge of estrogen to stimulate breast cancer?
Expert: High estrogen breast cancer and pregnancy lactation no causal relationship
In the first three months of pregnancy, the pregnant woman's estrogen levels will quickly soared to 30-50 times the normal level, and with the increase of the month and rising. Breast cancer happens to be hormone responsive tumors, estrogen receptor pathway through the action of estrogen in breast ductal epithelial cells, in the case of excessive activation of the pathway, the rapid proliferation of mammary epithelial cells can be cancerous. So there was speculation that high estrogen levels during pregnancy might stimulate breast cancer is the "culprit"!
In this regard, Rao Nanyan doctors can not agree. She pointed out that the hormone estrogen is the external cells need to grow by estrogen receptor to signal to the breast cells, promoting cell proliferation, differentiation, division, is something that the body needs for growth, rather than risk factors . For breast cancer, an increase in estrogen is a risk factor, but not the direct cause. Human health by the combined effects of a variety of hormones, in addition to increased estrogen, progesterone and other hormones also increased rapidly during pregnancy, but progesterone is protective factors that can play with estrogen antagonism
Breast younger, had breast cancer women also born children?
Would deprive part of fertility treatment in breast cancer patients
Overseas studies have shown that systemic therapy after breast cancer incidence of permanent amenorrhea ranged from 33% to 76%. Currently have a greater impact on ovarian function in patients with breast cancer, chemotherapy, radiotherapy, endocrine therapy, patients may lose fertility after chemotherapy. Some people even after fertility treatment also has the ability to inspire them due to the fear of breast cancer recurrence pregnancy also deterred pregnant
Choose fertility patients should avoid relapse peak period
According饶南燕of physicians, patients should stop hormonal therapy more than six months, through the drug washout period of pregnancy can be selected. There are different subtypes of breast cancer recurrence peak, patient selection before pregnancy should consult a physician to avoid the peak time of recurrence: relapse peak Her-2 positive breast cancer patients within two years; ER or PR strongly positive relapse in patients with a peak five years later, eight to 10 years, when the highest recurrence rate; relapse peak triple negative breast cancer is 3 to 5 years